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What are the factors cause sperm deformity

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Normal sperm is less than 15%6 affiliated hospital of zhongshan university Wang Zhong uropoiesis surgical department director Yang said, deformed sperm too much disease, is refers to the abnormal morphology sperm percentage too much of a disease.Deformed sperm does not have ability to normal activities and conception, is one of the main causes of male infertility.In normal semen, in addition to the normal sperm, contains a certain percentage of abnormal sperm, the latest in the WHO manual regulation in the form of human sperm normal reference range minimum standard is 4%, however, related data from assisted reproductive technology project shows that, if the normal morphology sperm is lower than 15%, in vitro fertilization rate is low.A man's sperm: in conventional semen analysis, determination of sperm morphology sperm fertilised the prediction ability of the most valuable, but the sperm morphology evaluation is less likely to do accurate and stable, because human sperm itself exists the situation of morphological diversity, and morphologic detection affected by detection of subjective bias.Sperm malformation test and count shall, according to the WHO standards recommended by the dyeing method and the counting method, and to strictly grasp the standard of normal sperm morphology and sperm deformity classification criteria.Abnormal sperm number one by oneSperm malformation has a variety of situations, the first is abnormal sperm head.Sperm head main structure for the enrichment of the nucleus and acrosome.In abnormal chromatin mature process can lead to the head of the sperm nuclear vacuoles sample defects or abnormal sperm nuclear risk is higher.Wang Zhong Yang said that there were relatively rare round-headed sperm syndrome, show the appearance of the sperm head is round, acrosome without missing, too small, or from, no density after acrosome zone, but also of the familial.Another kind is abnormal sperm neck and in the middle.Head to tail separation is a common connection section of sperm deformity, such abnormality is also called beheaded sperm.Studies have found that most beheaded normal sperm tail structure;A small percentage of this kind of sperm, the tail had connection section and cytoplasmic cloud of package, or lack of present middle;Another part of the sperm, the tail has a connection section and the middle of the rules of the or connected to the main section of the remaining connection segment.Wang Zhong Yang believes that too much residual cytoplasm may lead to reduced sperm function.Also is a kind of abnormal sperm flagellum.Mainly include primary ciliary dyskinesia and fibrous sheath dysplasia two kinds of performance, the former is an autosomal recessive genetic disease.These patients are often characterized by bronchiectasis, chronic sinusitis, situs inversus and male infertility.Cilia or flagella structure can't effectively swing is its main causes.While the latter is common in severe weak sperm, most of the sperm tail short by optical microscopy, stiff, thick or irregular.Eat more soy yam sperm more benefitWang Zhong young said, affect sperm morphology and sperm deformity caused mechanism is not entirely clear, but on the whole mainly includes microbiological, physical and chemical factors and several aspects, such as endocrine factors.





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